New research indicates that people with insomnia who take melatonin supplements for over a year may face an increased risk of heart failure compared to those who do not use this common sleep aid.
The study revealed that individuals using melatonin supplements long-term were more likely to be diagnosed with heart failure, require hospitalization due to the condition, or experience death from any cause.
This research is scheduled for presentation at the American Heart Association’s Scientific Sessions 2025 in New Orleans. However, the findings have not yet undergone peer review.
Researchers emphasized that the study does not prove a direct cause-and-effect link between melatonin use and heart failure risk, but the findings highlight potential safety concerns for extended supplement use.
They suggested that further investigation is necessary to fully understand the cardiovascular safety of melatonin.
Many melatonin supplements are available over-the-counter without prescription, often without regulation. This allows individuals to use them without medical supervision.
“Melatonin supplements may not be as harmless as commonly assumed.”
Author’s summary: Prolonged melatonin supplement use in insomnia patients may increase heart failure risk, urging more research and caution in unsupervised consumption.