NFL Picks and Predictions for Week 6
The NFL season continues with a highly anticipated slate of games in Week 6. Here are 3 plus-money bets to consider before kickoff.
By Spenser Davis, Published: Oct 12, 2025 · 8:30 AM EDT. Our NFL bold predictions went 2-1 last week, resulting in a +1.17 unit overall gain. Since Week 3, our picks are up 2.16 units.
Week 6 Predictions
- Fading the Colts offense may not be the wisest choice, but there is a case for doing so.
Indianapolis is averaging 3.39 points per drive, which would be the highest this century if they maintain this pace all season.
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Author's summary: NFL Week 6 plus-money bets analysis.
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